Recherches et études scientifiques

Vous trouverez ci-dessous une liste de liens internet vous dirigeant à de multiples études portant sur les causes, les problèmes de santé physique et sur les traitements liés aux  approches biomédicales. Parmi les sujets traités vous trouverez, les toxines environnementales, les infections, l’inflammation, les régimes alimentaires, la grossesse, la prévalence, pour en nommer que quelques-uns. Cette liste n’est pas exhaustive. Certaines études sont seulement disponibles en anglais.

RECHERCHES SUR LES CAUSES DE L’AUTISME

Recherches sur la santé prénatale

The role of oxidative stress, inflammation and acetaminophen exposure from birth to early childhood in the induction of autism

http://journals.sagepub.com/doi/pdf/10.1177/0300060517693423

Acetaminophen use in pregnancy and neurodevelopment: attention function and autism spectrum symptoms

https://www.ncbi.nlm.nih.gov/pubmed/27353198

Elevated Maternal C-Reactive Protein and Autism in a National Birth Cohort

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633612/

Month of Conception and Learning Disabilities: A Record-Linkage Study of 801,592 Children

https://www.ncbi.nlm.nih.gov/pubmed/27651381

Maternal Infection During Pregnancy and Autism Spectrum Disorders

http://www.princeton.edu/~sswang/zerbo_croen13_maternal-infection-ASD_JADD.pdf

A sexually dichotomous, autistic-like phenotype is induced by Group B Streptococcus maternofetal immune activation

https://www.ncbi.nlm.nih.gov/pubmed/27220806

Extremely Preterm Born Children at Very High Risk for Developing Autism Spectrum Disorder

https://www.ncbi.nlm.nih.gov/pubmed/26546379

Association of Maternal Diabetes With Autism in Offspring

http://jamanetwork.com/journals/jama/fullarticle/2247143

Association of Perinatal Risk Factors with Autism Spectrum Disorder

https://www.thieme-connect.de/DOI/DOI?10.1055/s-0036-1597624

Gestational vitamin D deficiency and autism spectrum disorder

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385921/

Vitamin D treatment during pregnancy prevents autism-related phenotypes in a mouse model of maternal immune activation

https://molecularautism.biomedcentral.com/articles/10.1186/s13229-017-0125-0

Risk for Autism Spectrum Disorders According to Period of Prenatal Antidepressant Exposure

http://jamanetwork.com/journals/jamapediatrics/article-abstract/2616362

Diagnosed autism linked to maternal grandmother’s smoking in pregnancy 

http://www.bristol.ac.uk/news/2017/april/grandmaternal-smoking-and-autism.html

Fetal and postnatal metal dysregulation in autism

https://www.nature.com/articles/ncomms15493.pdf

Prenatal fever and autism risk

http://www.nature.com/mp/journal/vaop/ncurrent/pdf/mp2017119a.pdf?foxtrotcallback=true

Antidepressants during pregnancy and autism in offspring: population based cohort study

http://www.bmj.com/content/bmj/358/bmj.j2811.full.pdf

Too Much Folate in Pregnant Women Increases Risk for Autism, Study Suggests

http://www.jhsph.edu/news/news-releases/2016/too-much-folate-in-pregnant-women-increases-risk-for-autism-study-suggests.html


Rôle des toxines environnementales

Prenatal exposure to common environmental factors affects brain lipids and increases risk of developing autism spectrum disorders    

http://autisme-montreal.com/wp-content/uploads/2015/11/expectantmoms-chemicals.pdf

Air toxics and the risk of autism spectrum disorder: the results of a population based case-control study in southwestern Pennsylvania.

 https://www.ncbi.nlm.nih.gov/pubmed/26444407

Environmental toxicants and autism spectrum disorders: a systematic review

http://www.nature.com/tp/journal/v4/n2/full/tp20144a.html

L’exposition aux contaminants environnementaux et les troubles du spectre de l’autisme

http://www.rnetsa.ca/wp-content/uploads/2014/12/Contaminants-et-autisme.pdf

Autism spectrum disorder: interaction of air pollution with the MET receptor tyrosine kinase gene.

https://www.ncbi.nlm.nih.gov/pubmed/24240654

Neurodevelopmental Disorders and Prenatal Residential Proximity to Agricultural Pesticides: The CHARGE Study

https://ehp.niehs.nih.gov/wp-content/uploads/122/10/ehp.1307044.alt.pdf

Project TENDR: Targeting Environmental Neuro-Developmental Risks. The TENDR Consensus Statement

https://ehp.niehs.nih.gov/wp-content/uploads/124/7/EHP358.alt.pdf

Neurodevelopmental effects in children associated with exposure to organophosphate pesticides: a systematic review

https://www.ncbi.nlm.nih.gov/pubmed/24121005

Burden of disease and costs of exposure to endocrine disrupting chemicals in the European Union: an updated analysis.

https://www.ncbi.nlm.nih.gov/pubmed/27003928

Polychlorinated Biphenyl and Organochlorine Pesticide Concentrations in Maternal Mid-Pregnancy Serum Samples: Association with Autism Spectrum Disorder and Intellectual Disability

https://ehp.niehs.nih.gov/wp-content/uploads/advpub/2016/8/EHP277.acco.pdf

Neurobehavioural eff ects of developmental toxicity 

http://www.thelancet.com/pdfs/journals/laneur/PIIS1474-4422(13)70278-3.pdf

Pandemic of idiopathic multimorbidity

http://autisme-montreal.com/wp-content/uploads/2015/12/Can-Fam-Phys-Multimorbidity-Commentary.pdf


 Recherches sur la génétiques

Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440679/

A Twin Study of Heritable and Shared Environmental Contributions to Autism

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104233/

Advances in research (liste d’études liées à la génétique)

https://www.autism.com/advocacy_research_1#Genetics


Recherches sur l’immunologie et l’inflammation 

Evidence linking oxidative stress, mitochondrial dysfunction, and inflammation in the brain of individuals with autism.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001006/

Is a Subtype of Autism an Allergy of the Brain?

http://www.clinicaltherapeutics.com/article/S0149-2918(13)00182-3/pdf


Problèmes de santé physique liés à l’autisme

Medical Comorbidities in Autism Spectrum Disorders

http://autismcanada.org/wp-content/uploads/2015/04/Medical-Comorbidities-Report_July2014.pdf

Comorbidités relatives aux troubles du spectre de l’autisme

http://autisme-montreal.com/wp-content/uploads/2015/12/Comorbidities-Report_FR_2014.pdf

Advances in Research (inclut d’autres recherches intéressantes sur de multiples sujets)

https://www.autism.com/advocacy_research_1

Advances in Research – Part 2 (inclut d’autres recherches intéressantes sur de multiples sujets)

https://www.autism.com/tools_research_refs_pt2

Gastrointestinal Symptoms in Autism Spectrum Disorder: A Meta-analysis

http://pediatrics.aappublications.org/content/133/5/872

Study: Vitamin B12 levels low in brains affected by autism or schizophrenia

https://www.autismspeaks.org/science/science-news/study-vitamin-b12-levels-low-brains-affected-autism-or-schizophrenia

Elevated levels of tissue plasminogen activator and E-selectin in male children with autism spectrum disorder

https://www.ncbi.nlm.nih.gov/pubmed/27194368

Predictors of Self-Injurious Behavior and Self-Restraint in Autism Spectrum Disorder: Towards a Hypothesis of Impaired Behavioral Control

https://link.springer.com/article/10.1007%2Fs10803-016-3000-5

Gastrointestinal dysfunctions as a risk factor for sleep disorders in children with idiopathic autism spectrum disorder: A retrospective cohort study 

http://journals.sagepub.com/doi/abs/10.1177/1362361316667061

Shorter sleep duration is associated with social impairment and comorbidities in ASD  

https://www.ncbi.nlm.nih.gov/pubmed/28301091


Traitements Biomédicaux

Résumé des traitements diététiques, nutritionnels et médicaux pour l’autisme – basé sur plus de 150 études publiées

http://autisme-montreal.com/wp-content/uploads/2015/12/SummaryofTreatmentsforAutism-FR-2013.pdf

Summary of Dietary, Nutritional, and Medical Treatments for Autism – based on over 150 published research studies.

http://ariconference.com/enews/treatment.pdf

Autism and Dietary Therapy: Case Report and Review of the Literature

http://www.marthaherbert.org/library/AutismDietGFCFKetogenic-JChildNeurol-2013-HerbertBuckley-975-82.pdf

Randomized controlled trial of vitamin D supplementation in children with autism spectrum disorder

http://onlinelibrary.wiley.com/doi/10.1111/jcpp.12652/abstract;jsessionid=23CC13D4E1B5C2927C12B49C8E42EAA2.f01t03?systemMessage=Wiley+Online+Library+will+be+unavailable+on+Saturday+17th+December+2016+at+09%3A00+GMT%2F+04%3A00+EST%2F+17%3A00+SGT+for+4hrs+due+to+essential+maintenance.Apologies+for+the+inconvenience

Unexpected improvement in core autism spectrum disorder symptoms after long-term treatment with probiotics

https://www.ncbi.nlm.nih.gov/pubmed/27621806

Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study

http://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-016-0225-7

Is autism reversible?

http://autisme-montreal.com/wp-content/uploads/2015/12/Acta-Paed-Is-Autism-Reversible.pdf

Celiac Disease Presenting as Autism

http://autisme-montreal.com/wp-content/uploads/2015/12/J-Child-Neurology-Autism-Celiac.pdf


Nutrition et diète spéciale

Markers of Celiac Disease and Gluten Sensitivity in Children with Autism

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688832/

Autism and Dietary Therapy: Case Report and Review of the Literature

http://www.marthaherbert.org/library/AutismDietGFCFKetogenic-JChildNeurol-2013-HerbertBuckley-975-82.pdf

Celiac disease presenting as autism

https://www.ncbi.nlm.nih.gov/pubmed/19564647


 Prévalence

Estimated Prevalence of Autism and Other Developmental Disabilities Following Questionnaire Changes in the 2014 National Health Interview Survey

https://www.cdc.gov/nchs/data/nhsr/nhsr087.pdf

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