Scientific Research and Studies

RESEARCH ON THE CAUSES OF AUTISM 

Research on prenatal health 

Prevalence of Autism Spectrum Disorder in Preterm Infants: A Meta-analysis
https://www.ncbi.nlm.nih.gov/pubmed/30076190

Prenatal and perinatal risk factors and the clinical implications on autism spectrum disorder.
https://www.ncbi.nlm.nih.gov/pubmed/29950101

Polycystic ovary syndrome and autism: A test of the prenatal sex steroid theory

https://www.nature.com/articles/s41398-018-0186-7

Dynamical features in fetal and postnatal zinc-copper metabolic cycles predict the emergence of autism spectrum disorder

http://advances.sciencemag.org/content/4/5/eaat1293.full

Prenatal fever and autism risk

https://www.nature.com/articles/mp2017119

Prenatal Exposure to Acetaminophen and Risk for Attention Deficit Hyperactivity Disorder and Autistic Spectrum Disorder: A Systematic Review, Meta-Analysis, and Meta-Regression Analysis of Cohort Studies

https://academic.oup.com/aje/advance-article-abstract/doi/10.1093/aje/kwy086/4980325?redirectedFrom=fulltext

Thyroid-disrupting chemicals and brain development: an update

http://www.endocrineconnections.com/content/7/4/R160.full.pdf+html

Association of Maternal Use of Folic Acid and Multivitamin Supplements in the Periods Before and During Pregnancy With the Risk of Autism Spectrum Disorder in Offspring

https://jamanetwork.com/journals/jamapsychiatry/article-abstract/2667432?redirect=true

Prenatal exposure to acetaminophen and children’s language development at 30 months

http://www.europsy-journal.com/article/S0924-9338(17)32989-9/fulltext

Social impairments in autism spectrum disorder are related to maternal immune history profile

https://www.nature.com/articles/mp2017201.pdf

Antenatal nutritional supplementation and autism spectrum disorders in the Stockholm youth cohort: population based cohort study

http://www.bmj.com/content/359/bmj.j4273

Combined Prenatal Pesticide Exposure and Folic Acid Intake in Relation to Autism  Spectrum Disorder

https://ehp.niehs.nih.gov/wp-content/uploads/2017/09/EHP604.alt_.pdf

The role of oxidative stress, inflammation and acetaminophen exposure from birth to early childhood in the induction of autism

http://journals.sagepub.com/doi/pdf/10.1177/0300060517693423

Acetaminophen use in pregnancy and neurodevelopment: attention function and autism spectrum symptoms

https://www.ncbi.nlm.nih.gov/pubmed/27353198

Elevated Maternal C-Reactive Protein and Autism in a National Birth Cohort

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633612/

Month of Conception and Learning Disabilities: A Record-Linkage Study of 801,592 Children

https://www.ncbi.nlm.nih.gov/pubmed/27651381

Maternal Infection During Pregnancy and Autism Spectrum Disorders

http://www.princeton.edu/~sswang/zerbo_croen13_maternal-infection-ASD_JADD.pdf

A sexually dichotomous, autistic-like phenotype is induced by Group B Streptococcus maternofetal immune activation

https://www.ncbi.nlm.nih.gov/pubmed/27220806

Extremely Preterm Born Children at Very High Risk for Developing Autism Spectrum Disorder

https://www.ncbi.nlm.nih.gov/pubmed/26546379

Association of Maternal Diabetes With Autism in Offspring

http://jamanetwork.com/journals/jama/fullarticle/2247143

Association of Perinatal Risk Factors with Autism Spectrum Disorder

https://www.thieme-connect.de/DOI/DOI?10.1055/s-0036-1597624

Risk for Autism Spectrum Disorders According to Period of Prenatal Antidepressant Exposure

http://jamanetwork.com/journals/jamapediatrics/article-abstract/2616362

Antidepressants during pregnancy and autism in offspring: population based cohort study

http://www.bmj.com/content/bmj/358/bmj.j2811.full.pdf

Too Much Folate in Pregnant Women Increases Risk for Autism, Study Suggests

http://www.jhsph.edu/news/news-releases/2016/too-much-folate-in-pregnant-women-increases-risk-for-autism-study-suggests.html


Role of environmental toxins in autism

Neurobehavioral Deficits, Diseases, and Associated Costs of Exposure to Endocrine-Disrupting Chemicals in the European Union

Self-reported pregnancy exposures and placental DNA methylation in the MARBLES prospective autism sibling study

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538262/

Environment and Autism: Current State of the Science

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955700/pdf/nihms780807.pdf

Neurodevelopmental Disorders and Environmental Toxicants: Epigenetics as an Underlying Mechanism

https://www.hindawi.com/journals/ijg/2017/7526592/

Prenatal exposure to common environmental factors affects brain lipids and increases risk of developing autism spectrum disorders

http://autisme-montreal.com/wp-content/uploads/2015/11/expectantmoms-chemicals.pdf

Air toxics and the risk of autism spectrum disorder: the results of a population based case-control study in southwestern Pennsylvania.

https://www.ncbi.nlm.nih.gov/pubmed/26444407

Environmental toxicants and autism spectrum disorders: a systematic review

http://www.nature.com/tp/journal/v4/n2/full/tp20144a.html

L’exposition aux contaminants environnementaux et les troubles du spectre de l’autisme

http://www.rnetsa.ca/wp-content/uploads/2014/12/Contaminants-et-autisme.pdf

Autism spectrum disorder: interaction of air pollution with the MET receptor tyrosine kinase gene.

https://www.ncbi.nlm.nih.gov/pubmed/24240654

Neurodevelopmental Disorders and Prenatal Residential Proximity to Agricultural Pesticides: The CHARGE Study

https://ehp.niehs.nih.gov/wp-content/uploads/122/10/ehp.1307044.alt.pdf

Project TENDR: Targeting Environmental Neuro-Developmental Risks. The TENDR Consensus Statement

https://ehp.niehs.nih.gov/wp-content/uploads/124/7/EHP358.alt.pdf

Neurodevelopmental effects in children associated with exposure to organophosphate pesticides: a systematic review

https://www.ncbi.nlm.nih.gov/pubmed/24121005

Burden of disease and costs of exposure to endocrine disrupting chemicals in the European Union: an updated analysis.

https://www.ncbi.nlm.nih.gov/pubmed/27003928

Polychlorinated Biphenyl and Organochlorine Pesticide Concentrations in Maternal Mid-Pregnancy Serum Samples: Association with Autism Spectrum Disorder and Intellectual Disability

https://ehp.niehs.nih.gov/wp-content/uploads/advpub/2016/8/EHP277.acco.pdf

Neurobehavioural eff ects of developmental toxicity

http://www.thelancet.com/pdfs/journals/laneur/PIIS1474-4422(13)70278-3.pdf

Pandemic of idiopathic multimorbidity

http://autisme-montreal.com/wp-content/uploads/2015/12/Can-Fam-Phys-Multimorbidity-Commentary.pdf


Research on genetics

Psychophysiological Associations with Gastrointestinal Symptomatology in Autism Spectrum Disorder

http://onlinelibrary.wiley.com/doi/10.1002/aur.1646/abstract;jsessionid=94891AF71F57A30607403723CE0B380D.f04t04

Kctd13 deletion reduces synaptic transmission via increased RhoA

https://www.nature.com/articles/nature24470

Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440679/

A Twin Study of Heritable and Shared Environmental Contributions to Autism

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104233/

Advances in Research (list of studies on genetics)

https://www.autism.com/advocacy_research_1#Genetics


Research on immunology and inflammation

Evidence linking oxidative stress, mitochondrial dysfunction, and inflammation in the brain of individuals with autism.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001006/

Is a Subtype of Autism an Allergy of the Brain?

http://www.clinicaltherapeutics.com/article/S0149-2918(13)00182-3/pdf

 


Physical health problems related to autism

Medical Comorbidities in Autism Spectrum Disorders

http://autismcanada.org/wp-content/uploads/2015/04/Medical-Comorbidities-Report_July2014.pdf

Comorbidités relatives aux troubles du spectre de l’autisme

http://autisme-montreal.com/wp-content/uploads/2015/12/Comorbidities-Report_FR_2014.pdf

Advances in Research  (includes other interesting research on multiple topics)

https://www.autism.com/advocacy_research_1

Advances in Research – Part 2 (includes other interesting research on multiple topics)

https://www.autism.com/tools_research_refs_pt2

Advances in Research – Part 3 (includes other interesting research on multiple topics)

https://www.autism.com/tools_research_refs_pt3

Gastrointestinal Symptoms in Autism Spectrum Disorder: A Meta-analysis

http://pediatrics.aappublications.org/content/133/5/872

Study: Vitamin B12 levels low in brains affected by autism or schizophrenia

https://www.autismspeaks.org/science/science-news/study-vitamin-b12-levels-low-brains-affected-autism-or-schizophrenia

Elevated levels of tissue plasminogen activator and E-selectin in male children with autism spectrum disorder

https://www.ncbi.nlm.nih.gov/pubmed/27194368

Shorter sleep duration is associated with social impairment and comorbidities in ASD  

https://www.ncbi.nlm.nih.gov/pubmed/28301091


Biomedical treatments

Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794882/

Résumé des traitements diététiques, nutritionnels et médicaux contre l’autisme – basé sur plus de 150 études publiées

http://autisme-montreal.com/wp-content/uploads/2015/12/SummaryofTreatmentsforAutism-FR-2013.pdf

Summary of Dietary, Nutritional, and Medical Treatments for Autism – based on over 150 published research studies.

http://ariconference.com/enews/treatment.pdf

Autism and Dietary Therapy: Case Report and Review of the Literature

http://www.marthaherbert.org/library/AutismDietGFCFKetogenic-JChildNeurol-2013-HerbertBuckley-975-82.pdf

Randomized controlled trial of vitamin D supplementation in children with autism spectrum disorder

http://onlinelibrary.wiley.com/doi/10.1111/jcpp.12652/abstract;jsessionid=23CC13D4E1B5C2927C12B49C8E42EAA2.f01t03?systemMessage=Wiley+Online+Library+will+be+unavailable+on+Saturday+17th+December+2016+at+09%3A00+GMT%2F+04%3A00+EST%2F+17%3A00+SGT+for+4hrs+due+to+essential+maintenance.Apologies+for+the+inconvenience

Unexpected improvement in core autism spectrum disorder symptoms after long-term treatment with probiotics

https://www.ncbi.nlm.nih.gov/pubmed/27621806

Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study

http://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-016-0225-7

Is autism reversible?

http://autisme-montreal.com/wp-content/uploads/2015/12/Acta-Paed-Is-Autism-Reversible.pdf

Celiac Disease Presenting as Autism

http://autisme-montreal.com/wp-content/uploads/2015/12/J-Child-Neurology-Autism-Celiac.pdf

 

 


Nutrition and special diets

Comprehensive Nutritional and Dietary Intervention for Autism Spectrum Disorder—A Randomized, Controlled 12-Month Trial

http://www.mdpi.com/2072-6643/10/3/369/htm

Markers of Celiac Disease and Gluten Sensitivity in Children with Autism

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688832/

Autism and Dietary Therapy: Case Report and Review of the Literature

http://www.marthaherbert.org/library/AutismDietGFCFKetogenic-JChildNeurol-2013-HerbertBuckley-975-82.pdf

Celiac disease presenting as autism

https://www.ncbi.nlm.nih.gov/pubmed/19564647


Prevalence

Estimated Prevalence of Autism and Other Developmental Disabilities Following Questionnaire Changes in the 2014 National Health Interview Survey

https://www.cdc.gov/nchs/data/nhsr/nhsr087.pdf


 

Other Studies

Prevalence of Depressive Disorders in Individuals with Autism Spectrum Disorder: a Meta-Analysis

https://link.springer.com/article/10.1007%2Fs10802-018-0402-1

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